Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Sep 2008
Review Meta AnalysisPregabalin as a treatment for painful diabetic peripheral neuropathy: a meta-analysis.
Painful diabetic peripheral neuropathy (DPN) is an increasingly prevalent disorder that is best managed through a multimodal approach. We examined the effects of pregabalin on pain control, sleep disturbance, and the patient's global impression of change (PGIC) for the treatment of this disorder. ⋯ Pregabalin has significant effects on the pain associated with DPN as well as secondary endpoints that affect patients' quality of life.
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Reg Anesth Pain Med · Sep 2008
Multicenter Study Comparative StudyComplications associated with eye blocks and peripheral nerve blocks: an american society of anesthesiologists closed claims analysis.
Concern for block-related injury and liability has dissuaded many anesthesiologists from using regional anesthesia for eye and extremity surgery, despite many studies demonstrating the benefits of regional over general anesthesia. To determine injury patterns and liability associated with eye and peripheral nerve blocks, we re-examined the American Society of Anesthesiologists Closed Claims Database as part of the American Society of Regional Anesthesia and Pain Medicine's Practice Advisory on Neurologic Complications of Regional Anesthesia and Pain Medicine. ⋯ Performance of eye blocks by anesthesiologists significantly alters their liability profile, primarily related to permanent eye damage from block needle trauma. Though most peripheral nerve block claims are associated with temporary injuries, local anesthetic toxicity is a major cause of death or brain damage in these claims.
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Reg Anesth Pain Med · Sep 2008
ReviewPathophysiology of peripheral nerve injury during regional anesthesia.
Despite attention to technical details in performance of regional anesthetics, damage to nerves continues to be a concern. Understanding of pathophysiological mechanisms may aid in decreasing the incidence and severity of such injuries. ⋯ The relative importance of these pathogenic factors in cases of nerve injury after regional anesthesia is not resolved.