Regional anesthesia and pain medicine
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Reg Anesth Pain Med · May 2012
Randomized Controlled TrialAddition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial.
Pregabalin is often used as a perioperative analgesic adjunct; some studies show benefit, but others do not. Adverse effects, such as confusion and sedation, have been attributed to perioperative use of pregabalin. We tested the hypothesis that pregabalin, when used as part of a multimodal analgesic regimen, reduces the duration of moderate to severe pain in the first 24 hrs following foot or ankle surgery. Secondary outcomes included measures of opioid and pregabalin adverse effects. ⋯ No clinical benefit was obtained from perioperative administration of pregabalin (100 mg preoperative, then 50 mg every 12 hrs) as part of a multimodal postoperative analgesic regimen following foot and ankle surgery.
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Reg Anesth Pain Med · May 2012
Biography Historical ArticleCarl Koller, cocaine, and local anesthesia: some less known and forgotten facts.
Modern-day local anesthesia began in 1884 with a discovery by a young unknown ophthalmologist from Vienna named Carl Koller, who placed a cocaine solution on the cornea, thus producing insensibility. The news of his discovery spread throughout the world in less than a month. "Not surprisingly," a controversial priority discussion emerged. ⋯ In addition, Carl Koller's decision to leave Vienna is also surrounded in secrecy. The story surrounding the revelation of the local anesthetic effect of cocaine and the personalities involved is fascinating and relatively unknown.
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Reg Anesth Pain Med · May 2012
Comparative StudyThe effects of fluid injection on lesion size during bipolar radiofrequency treatment.
The effect of preinjected fluid on bipolar radiofrequency (RF) lesion characteristics has not been investigated with conventional pain medicine equipment. The purpose of the present study was to determine the effect of preinjected fluid composition on lesion parameters. ⋯ Fluid composition influences success, alters lesion size, and could be an appropriate consideration when selecting treatment parameters for bipolar RF. The enhanced lesion size and improved odds of producing a successful lesion with increasing NaCl concentration suggest a method to enlarge lesion size in a controlled manner.
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Reg Anesth Pain Med · May 2012
The creation of an objective assessment tool for ultrasound-guided regional anesthesia using the Delphi method.
The assessment of technical skills in ultrasound-guided regional anesthesia is currently subjective and relies largely on observations of the trainer. The objective of this study was to develop a checklist to assess training progress and to detect training gaps in ultrasound-guided regional anesthesia using the Delphi method. ⋯ Using the Delphi method, a checklist and GRS were developed. These tools can serve as an objective means of assessing progress in ultrasound technical skills acquisition.
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Reg Anesth Pain Med · May 2012
Near-infrared tracking system for epidural catheter placement: a feasibility study.
Epidural catheters are routinely used in regional and obstetric anesthesia. The flexible catheter is advanced without imaging control into the epidural space, and coiling or kinking of the catheter may occur, compromising the effectiveness of epidural anesthesia. Potentially near-infrared (NER) light detection may help, tracking advancement of the catheter in the epidural space. ⋯ Many variables such as obesity, paravertebral and extraforaminal catheter locations, and intervening bony structures can impede the application of NER technology for epidural catheter placements. Further optimization of the technology for clinical use is necessary.