Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Aug 2019
Perioperative duloxetine for acute postoperative analgesia: a meta-analysis of randomized trials.
Multimodal analgesia is a fundamental part of modern surgery and enhanced recovery pathways. Duloxetine, a serotonin and norepinephrine reuptake inhibitor, has been validated for the treatment of chronic neuropathic pain. The evidence for duloxetine as an adjunct for the treatment of acute postoperative pain remains controversial. We conducted a meta-analysis to determine the efficacy of duloxetine in the acute perioperative setting. ⋯ CRD42019121416.
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Reg Anesth Pain Med · Jul 2019
Music versus midazolam during preoperative nerve block placements: a prospective randomized controlled study.
Music medicine is a non-pharmacologic intervention that is virtually harm-free, relatively inexpensive and has been shown to significantly decrease preoperative anxiety. In this study we aim to compare the use of music to midazolam as a preoperative anxiolytic prior to the administration of an ultrasound-guided single-injection peripheral nerve block. ⋯ Clinicaltrials.gov #NCT03069677.