Regional anesthesia and pain medicine
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Reg Anesth Pain Med · Jun 2019
Clinical TrialGreater analgesic effect with intermittent compared with continuous mode of lumbar plexus block for total hip arthroplasty: a randomized controlled trial.
Lumbar plexus block (LPB) is an effective perioperative analgesic therapy for patients undergoing total hip arthroplasty (THA). However, the analgesic efficacy of intermittent administration compared with continuous infusion of LPB in patients remains unclear. ⋯ Greater analgesic effect was achieved using the intermittent mode than the continuous mode of LPB administration.
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Reg Anesth Pain Med · Jun 2019
Response to BotulinumtoxinA in a migraine cohort with multiple comorbidities and widespread pain.
The phase III research evaluating migraine prophylaxis therapy (PREEMPT) protocol was developed in low-risk migraine patients. We studied longitudinal response to treatment in a sequential retrospective observational cohort to evaluate predictors of effectiveness in patients with multiple overlapping pain syndromes treated in a quaternary pain management clinic. ⋯ Our findings point to the importance of identifying and addressing pain interference and depression early in chronic migraine management and, more broadly, highlights the importance of multidisciplinary evaluation and treatment in chronic migraine.