Regional anesthesia and pain medicine
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Reg Anesth Pain Med
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Reg Anesth Pain Med · May 2015
Randomized Controlled TrialImpact of pregabalin on the occurrence of postthoracotomy pain syndrome: a randomized trial.
Postthoracotomy pain syndrome (PTPS) is a frequent cause of chronic postoperative pain. Pregabalin might reduce the incidence of chronic postoperative pain. The goal of this study was to evaluate the impact of perioperative pregabalin on the occurrence of PTPS, defined as any surgical site pain 3 months after surgery. ⋯ Pregabalin did not reduce the incidence of PTPS in this study. Future research on PTPS should focus on the impact of regional analgesia on central sensitization.