Regional anesthesia and pain medicine
The most recent articles from:
Reg Anesth Pain Med
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Reg Anesth Pain Med · May 2009
Bicarbonate plus epinephrine shortens the onset and prolongs the duration of sciatic block using chloroprocaine followed by bupivacaine in sprague-dawley rats.
Chloroprocaine is a fast-acting local anesthetic, whereas bupivacaine is a long-acting one. They have been coadministered with limited success. The objective of this study was to determine the effect of additives on the efficacy of regional blockade using chloroprocaine followed by bupivacaine. ⋯ Sodium bicarbonate plus epinephrine shortens the onset and prolongs the duration of a chloroprocaine-bupivacaine sciatic block in Sprague-Dawley rats.
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Reg Anesth Pain Med · May 2009
Comment Letter Case ReportsImmediate lipid emulsion therapy in the successful treatment of bupivacaine systemic toxicity.