Regional anesthesia and pain medicine
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Reg Anesth Pain Med · May 2006
Randomized Controlled Trial Comparative StudyComparison of analgesic methods for total knee arthroplasty: metabolic effect of exogenous glucose.
This study was set up to assess whether postoperative suppression of gluconeogenesis by dextrose infusion would be influenced by continuous peripheral nerve block (CPNB) with local anesthetics, in comparison with epidural and with intravenous analgesia. ⋯ Excellent analgesia was achieved in the epidural and continuous nerve block groups. Postoperative gluconeogenesis was totally suppressed by dextrose infusion independent of the analgesia technique with no change in glucose utilization.
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Reg Anesth Pain Med · May 2006
Infraorbital nerve block in children: a computerized tomographic measurement of the location of the infraorbital foramen.
Infraorbital nerve blocks are performed in children undergoing cleft-lip surgery and endoscopic sinus surgery. The nerve exits the maxilla at the level of the infraorbital foramen. A sensory block of the infraorbital nerve can be performed by use of an intraoral route or an extraoral route. The objective of this study was to derive a mathematical formula to determine the position of the infraorbital foramen. ⋯ Our study found a linear correlation with age to the distance of the infraorbital foramen. This anatomic knowledge of the location of the infraorbital foramen may facilitate correct positioning of the needle. Future studies on the use of this formula with anatomic coordinates should be performed to test the validity of this formula.
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Reg Anesth Pain Med · May 2006
Randomized Controlled Trial Comparative StudyPreemptive analgesia with bupivacaine for segmental mastectomy.
Preemptive analgesia is the concept of providing analgesia before surgical incision, resulting in less postoperative pain. The purpose of this study is to determine if preemptive and/or postoperative local anesthetic infiltration of bupivacaine in patients undergoing segmental mastectomy results in less postoperative pain compared with patients receiving placebo. ⋯ Preincisional and/or postoperative wound bupivacaine infiltration lacks preemptive analgesic effects for segmental mastectomy.
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Reg Anesth Pain Med · May 2006
Meta AnalysisThe analgesic effects of perioperative gabapentin on postoperative pain: a meta-analysis.
Gabapentin is an anticonvulsant that has been shown to be effective in the treatment of neuropathic and inflammatory pain in animal and human studies. The analgesic effect of its perioperative use has not been fully elucidated. ⋯ Based on this systematic review, perioperative oral gabapentin is a useful adjunct for the management of postoperative pain that provides analgesia through a different mechanism than opioids and other analgesic agents and would make a reasonable addition to a multimodal analgesic treatment plan.
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Reg Anesth Pain Med · May 2006
Randomized Controlled Trial Comparative StudyAnalgesic efficacy of two doses of intrathecal midazolam with bupivacaine in patients undergoing cesarean delivery.
In this prospective, randomized, double-blind, placebo-controlled study, we investigated the postoperative analgesic efficacy of 2 doses of intrathecal midazolam as an adjunct to bupivacaine for spinal anesthesia. ⋯ Intrathecal midazolam 2 mg provided a moderate prolongation of postoperative analgesia when used as an adjunct to bupivacaine in patients undergoing cesarean delivery. Intrathecal midazolam, 1 mg and 2 mg, decreased postoperative nausea and vomiting.