Langenbeck's archives of surgery
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Langenbecks Arch Surg · Oct 2014
Randomized Controlled Trial Multicenter StudyHemostatic efficacy of latest-generation fibrin sealant after hepatic resection: a randomized controlled clinical study.
This randomized, controlled, single-blinded multicenter study evaluated the efficacy of latest-generation fibrin sealant containing synthetic aprotinin as fibrinolysis inhibitor as supportive treatment for hemostasis after elective partial hepatectomy. ⋯ Fibrin sealant was shown to be safe and superior to manual compression in the control of parenchymal bleeding after hepatic resection. The use of synthetic aprotinin as fibrinolysis inhibitor further improves the safety margin of fibrin sealant by eliminating the risk of transmission of bovine spongiform encephalopathy and other bovine pathogens.
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Langenbecks Arch Surg · Oct 2014
Randomized Controlled TrialBipolar vessel sealing: instrument contamination and wear have little effect on seal quality and success in a porcine in vitro model.
The aim of this study is to systematically investigate under standardized experimental conditions the effects of instrument contamination and wear on the quality of bipolar vessel sealing (BVS) achieved using a reusable instrument. ⋯ The impact of bipolar forceps contamination and wear on seal success and quality was negligible in our in vitro model. To achieve high-quality seals, it is essential to use adequate sealing pressures. Our findings could have direct implications for the design and clinical handling of BVS instruments.
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Langenbecks Arch Surg · Aug 2014
Could hyponatremia be a marker of anastomotic leakage after colorectal surgery? A single center analysis of 1,106 patients over 5 years.
The aim of this study is to define the significance of hyponatremia as a marker of anastomotic leakage after colorectal surgery. ⋯ Hyponatremia could be a specific and relevant marker of anastomotic leakage after colorectal surgery. If hyponatremia and leukocytosis are present after colorectal surgery, anastomotic leakage should be suspected and a CT scan with rectal contrast dye is recommended.