Langenbeck's archives of surgery
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Langenbecks Arch Surg · Aug 2011
Clinical TrialTriclosan-coated sutures reduce wound infections after hepatobiliary surgery--a prospective non-randomized clinical pathway driven study.
Wound infections after abdominal surgery are still frequent types of nosocomial infections. Suture materials might serve as a vehicle for mechanical transport of bacteria into the surgical wound. To reduce bacterial adherence to surgical sutures, triclosan-coated polyglactin 910 suture materials with antiseptic activity (Vicryl plus®) were developed. The aim of this prospective non-randomized clinical pathway driven study was to ascertain if the use of Vicryl plus® reduced the number of wound infections after transverse laparotomy. ⋯ Antiseptic-coated loop Vicryl suture for abdominal wall closure can be superior to PDSII sutures in respect to the development of wound infections after a two-layered closure of transverse laparotomy.
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Langenbecks Arch Surg · Aug 2011
Clinical TrialBeneficial effects of theophylline infusions in surgical patients with intra-abdominal hypertension.
Intra-abdominal hypertension (IAH) can cause high mortality. Recently, we found that IAH was associated with increased serum levels of adenosine and interleukin 10. Our present "hypothesis-generated study" was based on the above mentioned results. ⋯ Adenosine receptor antagonism with T following IAH diagnosis resulted in markedly reduced mortality in patients with moderated IAH (<20 mmHg). Theophylline-associated mortality reduction may be related to improved renal perfusion and improved MAP, presumably caused by adenosine receptor blockade. Because this study was not a randomized controlled study, these compelling observations require further multicentric clinical confirmation.
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Langenbecks Arch Surg · Jun 2011
Comparative StudyWhich surgical procedure offers the best treatment for pilonidal disease?
Our aim was to determine the most effective surgical procedure for treatment of pilonidal disease, by comparing different surgical techniques. ⋯ Despite the increasing volume of data on the treatment of pilonidal disease, the optimal treatment has yet to be established.
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Langenbecks Arch Surg · Jun 2011
Practice GuidelineGerman Association of Endocrine Surgeons practice guidelines for the surgical treatment of benign thyroid disease.
Benign thyroid disorders are among the most common diseases in Germany, affecting around 15 million people and leading to more than 100,000 thyroid surgeries per year. Since the first German guidelines for the surgical treatment of benign goiter were published in 1998, abundant new information has become available, significantly shifting surgical strategy towards more radical interventions. Additionally, minimally invasive techniques have been developed and gained wide usage. These circumstances demanded a revision of the guidelines. ⋯ Evidence-based recommendations for the surgical treatment of benign thyroid diseases have been created to aid the surgeon and to support optimal patient care, based on current knowledge. These recommendations comply with the Association of the Scientific Medical Societies in Germany requirements for S2k guidelines.