Journal of medical economics
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Treatment of candidemia with echinocandins: data on hospital resource use from a real world setting.
Real-world data on patients treated with echinocandins for candidemia are limited. This study examined the effect of three echinocandin-based treatment regimens on resource utilization in patients with Candida infection. ⋯ Fluconazole before or after echinocandin was associated with significantly greater resource utilization than echinocandin use alone.
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Comparative Study
The cost to managed care of managing pulmonary hypertension.
To estimate direct medical costs and resource use for commercially-insured patients within two pulmonary hypertension sub-groups: pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). ⋯ CTEPH and PAH patients incurred higher costs and used more resources than controls in the baseline and follow-up periods.
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The aim of this analysis was to assess the cost-effectiveness of tapentadol PR (prolonged release) compared with oxycodone CR (controlled release) in severe non-malignant chronic pain patients in whom controlled release morphine was ineffective or not tolerated. ⋯ The cost-effectiveness study suggested that initiating 2nd line treatment in patients with severe non-malignant chronic pain in the UK with tapentadol instead of oxycodone improves patients' quality-of-life and is less costly. Key limitations when interpreting the results are the use of different sources to populate the model and restricted generalizability due to data extrapolation.
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Patients refractory to older therapies for neuropathic pain (NeP) have few remaining therapeutic options. This study evaluates the cost-utility of pregabalin in the treatment of patients with refractory neuropathic pain in Sweden, from a healthcare and a societal perspective. ⋯ This study found pregabalin combined with usual care to be cost-effective compared to usual care in patients with refractory NeP from a Swedish Health Care perspective. Moreover, sensitivity analysis showed pregabalin's cost-effectiveness to be robust in all scenarios modelled.
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More than 100,000 patients each year in Denmark experience nosocomial infections, erroneous medication, or pressure ulcers while hospitalized. The Danish Safer Hospital Program includes 12 bundles for improving patient safety through the introduction and maintenance of evidence-based routine treatment or standard procedures. ⋯ We found that implementation of VB is potentially cost-effective when considering prevention of one case of VAP or death, based on a Danish ICU as a case study.