Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
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Almost absent inflammtory reaction or unusually deep inflammation can lead to atypical varieties of dermatophytoses. Some of the more common varieties of this kind are briefly portrayed. The importance of mycological examination, both microscopic and cultural, is pointed out.
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Case Reports
[Clinical picture of pretibial myxedema and new aspects of diagnosis and pathogenesis].
We have reported on two cases of pretibial myxedema. In one patient, the pretibial myxedema developed symmetrically half a year after the appearance of endocrine exophthalmos. Recently, acropachy developed as well. ⋯ The thyreohypophyseal feedback mechanism in this syndrome was examined for the first time by means of TRH stimulation tests. In both patients, thyroid auto-antibodies indicative of autoimmune thyroiditis were demonstrated. A high activity of long acting thyroid stimulator was measured in the one patient's serum.
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This review considers the following melanocytic and nevocytic nevi: nevus spilus, cellular blue nevus, benign juvenile melanoma, mongolian spot and nevus of Ota. Clinical aspects, histopathology and prognosis are outlined, based on data from the recent literature.
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A screening test for urinary porphyrin excretion was performed amound 1433 diabetes patients (552 males and 881 females). In three patients (0.21)% the diagnosis of porphyria cutanea tarda was ascertained. ⋯ The sulfonylurea Oradian was the likely etiopathogenic factor in only one out of three patients. The above mentioned observations do not speak in favour of independent etiological porphyrinogenic influence of antidiabetic sulfonylurea drugs.
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A case of epidermolysis bullosa acquisita associated with colitis granulomatosa (Crohn's disease) is reported. Although the cutaneous lesions of this unusual disease resemble in their clinical, histological and ultrastructural features to those of the hereditary epidermolysis bullosa dystrophica, the epidermolysis bullosa acquisita has to be regarded as a separate entity among the blistering epidermolysis because of its late manifestation in adults without evidence of hereditary disorders. The deposits of immunoglobulins in the involved skin of the acral areas demonstrated fluorescentmicroscopically are discussed in regard of a possible etiopathogenic relation with the primary irritated intestinal disease.