Adv Clin Exp Med
-
Motor cortex stimulation is one of the neuromodulation methods of treating refractory central neurogenic pain. ⋯ MCS significantly reduces the intensity of neurogenic pain. The best long-term results in the present study were achieved in patients with thalamic syndrome. No significant predictors were found for a successful final outcome. The authors consider appropriate selection of patients, accurate placement of the electrodes and frequent adjusting of the stimulation parameters to be important factors increasing the efficacy of MCS.
-
Cystic fibrosis (CF) is a particular example of a chronic disease with progressive course. Current statistical data shows that the life span of patients with CF has extended. Therefore, it is necessary to undertake interdisciplinary actions aiming at improving the efficiency of medical activities as well as minimalizing the influence of those interventions on the patients' quality of prolonged life. ⋯ Patients with CF generally evaluate their QoL as low; there are differences in the evaluation of QoL between women and men. There is a relation between patients' QoL their age. The older the patient is, the worse his QoL in most subscales is.
-
Modern anticancer chemotherapy can cause numerous adverse effects in the organism, whose functioning has already been disrupted by the neoplastic process itself. ⋯ The findings of the current study regarding the toxicity of the FOLFOX-4 and CLF-1 therapy regimens should be taken into consideration when monitoring chemotherapy safety in colon cancer. The patients' tolerance of the administered medication and the side effects reported by patients should be constantly evaluated, which will help prevent these side effects, apply appropriate therapy and contribute to the improvement of the patients' quality of life. The functioning of the central nervous system should be carefully evaluated when planning the anticancer therapy, especially if repeated administration of neurotoxic drugs is necessary in cases of a recurrence of the disease. Chemotherapy should be thoroughly monitored for safety, especially in women over 65 years of age suffering from coexisting diseases. Colon cancer patients and their families should be informed of the risks of nutritional supplements before the start of the anticancer chemotherapy, and may need to dispense with their use.
-
Complications of type 2 diabetes (T2D) lead to increased mortality and reduced quality of life (QOL). ⋯ Both subjective and objective HRQoL in patients with T2D was lower than in respondents similar in age from the general population. Compared with type 2 diabetic populations from other countries, Polish patients are characterized by relatively high HRQoL objective assessment and very low subjective assessment.