Adv Exp Med Biol
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Randomized Controlled Trial Clinical Trial
A population-based trial of beta-carotene chemoprevention of head and neck cancer.
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This study examined the cardiovascular and oxygen transport/consumption relationships in haemorrhagic shock and resuscitation using Human Albumin and Gelatin solutions in a porcine haemorrhagic shock model. Immature pigs (17-25 kg) were anaesthetised and ventilated with nitrous oxide, oxygen and isoflurane. Aortic pressure monitoring and monitoring of pulmonary pressures and cardiac output via a Swan-Ganz catheter were instituted. ⋯ Deterioration was more rapid in the Gelatin group due to the estimated half a life of 3 hours in this model. Oxygen extraction was 10% higher in the Gelatin group 2 hours after resuscitation. The role of oxygen radicals in haemorrhagic shock is discussed.
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Comparative Study Clinical Trial
Evaluation of oxygenation with different modes of ventilation in patients with adult respiratory distress syndrome.