Indian J Med Res
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Standard treatment guidelines (STGs) are the cornerstone to therapeutics. Multiple agencies in India develop STGs. This systematic review was conducted to find out STGs available in India, evaluate if these were as per World Health Organization (WHO) recommendations for STGs and compare these with National Institute for Health and Care Excellence (NICE) guidelines. Information on legal authority and responsibility for formulating STGs was also sought. ⋯ In India, although there are multiple STGs developed by various authorities and professionals for the same conditions, these fulfil WHO recommendations only partially. Authority with statutory duty collaborating with professional organizations, a standard methodology for adopting international guidelines, Indian data for evidence base, attention to local needs will help in developing better STGs and their acceptance.
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Review Biography Historical Article
Jagdish Chandra Bose & plant neurobiology.
When Jagdish Chandra Bose, a renowned physicist, devoted himself entirely to research in the field of plant physiology post his superannuation at Presidency University, Kolkata, India (earlier known as Presidency College, Calcutta), it came as a surprise to many. The research on plant nervous system by JC Bose during this period was pioneering in nature, being recognized by recent plant biologists globally as the first in the field. ⋯ More than a hundred years later, recent advances in molecular biology, genomics, ecology and neurophysiology have led to renewed interest resulting in a flurry of activity, confirming most of Bose's observations. The present review describes this pioneering scientist's work and his immense contribution in the emergence of the discipline now designated as 'Plant Neurobiology'.
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Paediatric chronic myeloid leukaemia (CML) has biological and clinical differences from adult CML. Management of paediatric CML presents unique challenges in growing children, and there are no specific guidelines for paediatric CML. This review focusses on the clinical characteristics, diagnostic issues and management of paediatric CML. ⋯ Studies conducted on adult CML patients were used to guide the management of places where studies were lacking in paediatric CML. Recently, dasatinib and nilotinib have been approved for treatment of paediatric CML, and their role has been discussed in the current management perspective. Allogeneic transplant, fertility and vaccination in paediatric CML, have also been discussed.
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[This corrects the article DOI: 10.4103/ijmr. IJMR_1239_18].