Actas dermo-sifiliográficas
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Actas Dermosifiliogr · Jan 2014
Observational StudyNotalgia paresthetica: treatment using intradermal botulinum toxin A.
Notalgia paresthetica is a sensory mononeuropathy that affects dorsal segments T2 to T6. It can have a significant effect on quality of life. Numerous treatments have been used with variable results. ⋯ Botulinum toxin A appears to be a safe therapeutic option for patients with notalgia paresthetica. However, data currently available come from small patient series, making it difficult to draw definitive conclusions regarding the true efficacy and long-term effects of this treatment.
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Actas Dermosifiliogr · Dec 2013
Retrospective study of the clinical, histologic, and immunologic features of epidermolysis bullosa acquisita in 9 patients.
Epidermolysis bullosa acquisita (EBA) is an autoimmune subepidermal blistering disease caused by autoantibodies to type VII collagen. The clinical presentation is variable, with skin and mucosal lesions that can cause significant dysfunction. Different treatment options exist, but the results are often unsatisfactory. ⋯ EBA is a rare disease with a variable clinical presentation that can be confused with that of other subepidermal blistering diseases. Correct diagnosis requires a high level of clinical suspicion and the use of all available diagnostic tests. Thorough evaluation of cutaneous and mucosal involvement and prompt initiation of appropriate treatment will ensure the detection and prevention of dysfunction and treatment-related complications.
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Actas Dermosifiliogr · Nov 2013
Multicenter Study Observational StudyDemographic characteristics and health-related quality of life of patients with moderate-to-severe psoriasis: The VACAP study.
Psoriasis is associated with a deterioration in the health-related quality of life (HRQoL) of affected patients. The aim of this study was to assess the HRQoL of patients with moderate-to-severe psoriasis. ⋯ The principal factor related to HRQoL in patients with psoriasis is the severity of the disease.
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Actas Dermosifiliogr · Oct 2013
Multicenter Study Comparative Study Observational StudyImpact of active and stable psoriasis on health-related quality of life: the PSO-LIFE study.
The aim of this study was to assess the impact of psoriasis on health-related quality of life (HRQOL) using different questionnaires. ⋯ The impact of psoriasis on HRQOL is higher in patients with active disease. The PSO-LIFE questionnaire showed a greater tendency to discriminate between active and stable psoriasis than either the DLQI or the PDI. PSO-LIFE scores correlated significantly with lesion site and disease severity as measured by PASI.
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Actas Dermosifiliogr · Oct 2013
ReviewUpdate on the classification and treatment of localized scleroderma.
Morphea or localized scleroderma is a distinctive inflammatory disease that leads to sclerosis of the skin and subcutaneous tissues. It comprises a number of subtypes differentiated according to their clinical presentation and the structure of the skin and underlying tissues involved in the fibrotic process. However, classification is difficult because the boundaries between the different types of morphea are blurred and different entities frequently overlap. ⋯ With certain exceptions, the disorder does not have serious systemic repercussions, but it can cause considerable morbidity. In the case of lesions affecting the head, neurological and ocular complications may occur. There is no really effective and universal treatment so it is important to make a correct assessment of the extent and severity of the disease before deciding on a treatment approach.