Eur J Trauma Emerg S
-
Eur J Trauma Emerg S · Dec 2011
Risk factors associated with the development of post-traumatic retained hemothorax.
To identify risk factors associated with the development of post-traumatic retained hemothorax in chest trauma patients admitted to Hospital San Vicente de Paul (HUSVP). ⋯ The risk of post-traumatic retained hemothorax was associated with four factors. The probability of the outcome could be modified by careful monitoring, management protocols, suction through the tube thoracostomy, and maybe an early intervention, such as thoracoscopy.
-
Eur J Trauma Emerg S · Dec 2011
The Glue Grant experience: characterizing the post injury genomic response.
Despite ongoing improvements in resuscitation, care, and outcomes, traumatic injury remains a significant health care and economic burden. The causes are multifactorial, but our approach to the clinical management of these patients remains limited by our current understanding of the pathobiology of the disease. ⋯ The Program has not only successfully implemented clinical care guidelines for managing the severe trauma patient based on the best available evidence to minimize iatrogenic variability, but it has also examined the genome-wide, immune-inflammatory response in total and isolated blood leukocyte populations. This review will address current milestones as well as future directions for the Program.
-
Eur J Trauma Emerg S · Dec 2011
Polytrauma in the elderly: specific considerations and current concepts of management.
With an aging and more active older population, an increased incidence of elderly trauma patients, including severely injured geriatric patients, is anticipated. Poorer functional outcomes and increased mortality and morbidity rates in these patients compared to their younger counterparts may be inevitable due to the associated pre-existing medical conditions and the reduced physiological reserves and compensatory mechanisms secondary to aging. However, mortality and complication rates can be reduced, and outcomes can be improved, when prompt and aggressive treatment is provided. ⋯ In the herein study, the special needs of these patients and the current concepts on their management are summarised. Research in this field is ongoing in order to develop advanced management strategies to optimise outcomes. Overall, these patients should not be treated as "older adults", but as a special population with special considerations and the trauma care should be tailored to meet their specific needs.
-
Eur J Trauma Emerg S · Dec 2011
Mesenchymal stem cell (MSC) and endothelial progenitor cell (EPC) growth and adhesion in six different bone graft substitutes.
Several different synthetic and allograft bone graft substitutes are used clinically to treat large bone defects. In contrast to the "gold standard" of autologous bone grafts, these do not contain bone-forming (MSC) or vessel-forming (EPC) cells. In order to achieve the same level of success enjoyed by autologous bone grafts, they must be compatible with mesenchymal stem cells (MSC) and endothelial progenitor cells (EPC). In a previous study, we seeded MSC onto six different bone graft substitutes and then measured the cell adhesion, viability, differentiation, and morphology. In the present study, we seeded both MSC and EPC onto the same six bone graft substitutes and measured the same parameters. ⋯ When bone graft substitutes are used to help fill large defects, it is important that their interaction with these cells be supportive of bone healing.
-
Eur J Trauma Emerg S · Dec 2011
Endoscopic thoracic sympathectomy for posttraumatic complex regional pain syndrome.
Posttraumatic complex regional pain syndrome (CRPS) has a strongly negative impact on rehabilitation and activities of daily living. Treatment is most often unrewarding. ⋯ ETS is effective at decreasing pain and improving quality of life, and should therefore be considered in the treatment of CRPS.