J Trauma
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Although brain cooling has been reported to be effective in improving the outcome after traumatic brain injury (TBI) in rats, the mechanisms of brain cooling-induced neuroprotective actions remain unclear. This study was to test whether angiogenesis and neurogenesis attenuating TBI could be brain cooling stimulated. ⋯ Brain cooling-stimulated angiogenesis and neurogenesis attenuated a fluid percussion TBI in rats.
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Early prediction of massive transfusion (MT) is critical in the management of severely injured trauma patients. Variables available early after injury including physiologic, laboratory, and rotation thromboelastometric (ROTEM) parameters were evaluated as predictors for the need of MT. ⋯ Hemoglobin ≤ 10 g/dL and an abnormal maximum cloth firmness measured by rotation thromboelastometry on admission reliably predict the need for MT. Prospective validation of the effectiveness of thromboelastometry to guide the transfusion practice after trauma is warranted.
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Comparative Study
Comparison of plates versus intramedullary nails for fixation of displaced midshaft clavicular fractures.
We compare the use of plate and screws versus intramedullary nails in the operative management of patients with displaced midclavicular fractures. ⋯ Our results demonstrate no significant differences in functional outcome and nonunion rates between nails and plates fixation for displaced midshaft clavicular fractures.