Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Mar 2017
A comparison of the effects of platelet-rich plasma and demineralized bone matrix on critical bone defects: An experimental study on rats.
Delayed union of fractured bone is one of the main problems of orthopedics and traumatology practice. It was hypothesized that the beneficial effects of allogeneic platelet-rich plasma (PRP) would be valuable in the treatment of segmental bone defects. This study is a comparison of the effects of demineralized bone matrix (DBM) and PRP in a segmental bone defect model. ⋯ It was concluded that PRP and DBM have comparable effect on recovery of defective bones, but there is no synergistic effect when used together. We believe that PRP can be a cost-effective, readily available alternative to DBM with minimal morbidity.