Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Jun 2022
Neuroprotective effects of adrenomedullin in experimental traumatic brain injury model in rats.
Traumatic brain injuries cause damages in the brain in several ways, which include cell death because of edema, disruption of the blood-brain barrier, shear stress, and ischemia. In this study, we investigated the effects of adrenomedullin (AM) on oxidative stress and inflammation after head traumas in a rat model. ⋯ These results indicate that AM has neuroprotective effects on traumatic brain injury in a rat model.