Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Jan 2009
Tissue oxidative stress level and remote organ injury in two-hit trauma model of sequential burn injury and peritoneal sepsis are attenuated with N-acetylcysteine treatment in rats.
The second hit in trauma leads to an exaggerated inflammatory response and multiple organ failure. Infection following burn injury is a useful model for two-hit trauma studies. The aim of this study was to investigate the effect of N-acetylcysteine (NAC) treatment as an antioxidant in a two-hit trauma model. ⋯ NAC attenuated tissue oxidative stress level and remote organ injury in two-hit trauma. Further experimental and clinical studies on this subject are necessary.
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Ulus Travma Acil Cer · Jan 2009
Is the zeolite hemostatic agent beneficial in reducing blood loss during arterial injury?
Uncontrolled hemorrhage is the leading cause of fatality. The aim of this study was to evaluate the effect of zeolite mineral (QuikClot - Advanced Clotting Sponge [QC-ACS]) on blood loss and physiological variables in a swine extremity arterial injury model. ⋯ According to the physiological parameters, we observed that zeolite tends to reduce blood loss, however could not stop bleeding completely. We believe that further clinical trials are needed to conclude that zeolite could be used in the routine practice.
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Ulus Travma Acil Cer · Oct 2008
Review[War surgery in the 21st century: current approach to trauma cases].
Death caused by trauma is a major social problem in both the military and the civilian world. The goal is to reduce injuries and deaths to acceptable limits. ⋯ Significant changes have occurred recently in the treatment of trauma cases. In our study, we aimed to search the literature in order to describe the principles of proper medical approach, to review the operational strategies recommended in the field and to develop a consensus to the extent possible.
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Ulus Travma Acil Cer · Oct 2008
Comparative StudyA prospective and comparative study of referrals to neurosurgeons in an emergency department: does use of guidelines for head trauma affect the assessment made by non-neurosurgeons?
Restriction of the direct admission of all head-injured patients to the neurosurgical unit remains common practice in many parts of the world. This study was conducted to assess if the initial neurological examination of patients with a head trauma and their management are adequately performed before the referrals and also to determine whether strict use of guidelines for the management of patients with head injuries can be effective. ⋯ In hospitals where there are no specialist trauma surgeons, neurosurgeons should train non-neurosurgeons regarding the accurate selection of neurosurgical cases that need an emergency intervention. In this training, use of guidelines for the management of head injuries is very effective.
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Ulus Travma Acil Cer · Oct 2008
Should the New Injury Severity Score replace the Injury Severity Score in the Trauma and Injury Severity Score?
This study was performed to compare the efficacies of Injury Severity Score (ISS) and New Injury Severity Score (NISS), and to investigate whether replacing ISS with NISS in Trauma and Injury Severity Score (TRISS) changes the predictive power for mortality. ⋯ Use of NISS instead of ISS in the TRISS model demonstrated no significant difference, and it can thus be recommended for use.