Ulus Travma Acil Cer
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Ulus Travma Acil Cer · Feb 2023
Histopathological investigation of the effect of chitosan on oral mucous wound healing in experimentally established diabetic rats.
In our study, it was aimed to histopathologically investigate the effects of chitosan on wound healing in the oral mucosa by applying the gel form of experimentally induced diabetes mellitus. ⋯ It was observed that chitosan did not cause foreign body reaction in any of the groups on the 2nd and 5th days.
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Ulus Travma Acil Cer · Feb 2023
The determination of the protective role of sildenafil administration in rats with sepsis-induced liver injury.
Sepsis is a complex syndrome which comes out after infection, characterized by activation of inflammation and infection and has a high morbidity and mortality. Sildenafil (SLD) is a selective phosphodiesterase Type 5 enzyme inhibitor and is used in the treatment of erectile dysfunction effectively all over the world. In this study, we investigated whether SLD had protective effect or not by studying the effect of SLD on reactive oxygen species and antioxidants in cecal ligation and puncture (CLP) polymicrobial sepsis model in rat liver histopathologically and biochemically. ⋯ It was shown that acute SLD administration decreased liver damage in septic rats dose-dependently in this study. In addition, it was observed that it corrected the broken oxidant-antioxidant balance. This might mediate the protective effect of SLD in liver. However, we believe that new experimental and clinical studies should be in the future to understand the protective effect of SLD in liver.
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Ulus Travma Acil Cer · Feb 2023
ReviewCorrelation of important prognostic factors and CT scores in invasive and non-invasive ventilation of COVID-19 patients.
Intensive care workers received the largest share of the COVID-19 pandemic, which caused nightmares to the whole world. In COVID-19 pneumonia cases which had high mortality rates, many prognostic factors and laboratory examinations were tried to evaluate the clinical severity quickly and accurately.This study was planned to investigate a correlation between the initially ventilation strategy and major prognostic parameters and CT scores in patients admitted to intensive care unit (ICU). ⋯ Patients who started treatment with NIMV had relatively low poor prognostic factors, their mortality was lower. However, the total CT score at diagnosis was expected to be higher in those who were performed IMV, no significant difference was found in our study. We concluded that the severity classification of the patients cannot be made according to CT scores. CT results should be evaluated as a whole according to the patient's clinic, predisposing factors, and response to treatment.
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Ulus Travma Acil Cer · Feb 2023
ReviewThe effect of a new topographic classification on determining the prognosis of nasal fracture and treatment modality.
Classifications of nasal fracture are based on clinical findings or radiological findings. The classification systems of nasal fracture usually determine the type of nasal fracture. It is important that a classification gives information about treatment modality and prognosis rather than determining the type of fracture. The objective of this study was to show the effect of the new topographic classification on determining the parameters of prognosis and deciding on treatment modality of the nasal fracture. ⋯ We believe that the new topographic classification evaluates the parameters of clinical prognosis such as accompanying fracture, site of fracture and pattern of fracture, and also requirement of closed or open reduction better than other classifications.
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Ulus Travma Acil Cer · Feb 2023
Randomized Controlled TrialIs it necessary to use specimen retrieval bag for reducing surgical site infection in laparoscopic appendectomy?A randomized controlled trial.
The aim of the study was to investigate the comparison the effects of the extraction of specimen by using a specimen retrieval bag (SRB) or direct extraction through trochar in terms of surgical site infection (SSI) in patients who underwent laparoscopic appendectomy. ⋯ The results of the present study revealed that the use of SRB does not prevent microbial seeding in patients who underwent laparoscopic appendectomy; therefore, it was concluded that using SRB is not associated with SSI at laparoscopic appendectomy.