American journal of veterinary research
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Randomized Controlled Trial
Evaluation of the analgesic effect of intracameral lidocaine hydrochloride injection on intraoperative and postoperative pain in healthy dogs undergoing phacoemulsification.
To evaluate the intraoperative and postoperative analgesic effects of intracameral lidocaine hydrochloride injection in dogs undergoing phacoemulsification. ⋯ Intracameral lidocaine injection had significant analgesic effects in dogs undergoing cataract surgery. Results of this study suggest the value of intracameral lidocaine injection as an analgesic for intraocular surgery in dogs.
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Clinical Trial
Evaluation of electric neurostimulation to confirm correct placement of lumbosacral epidural injections in dogs.
To determine the minimal electric threshold (MET) of neurostimulation in and out of the lumbosacral epidural space necessary to cause muscle contraction of the hind limb or tail, determine an MET cutoff value that indicates epidural needle placement, and compare predictability of epidural needle placement attained by use of neurostimulation versus the standard technique that uses loss of resistance in dogs. ⋯ Neurostimulation is a useful tool to suggest correct lumbosacral epidural needle placement in dogs.
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To evaluate the effects of remifentanil on isoflurane minimum alveolar concentration (ISO(MAC)) in dogs. ⋯ Remifentanil decreased ISO(MAC) in a dose-related fashion; the reduction in ISO(MAC) was stable over the course of a prolonged CRI (6 hours). A dose of 0.30 microg of remifentanil/kg/min resulted in nearly maximal isoflurane-sparing effect in dogs; a ceiling effect was observed at higher infusion rates.
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To evaluate use of nonstyletted multiple-port catheters for epidural administration of ketamine hydrochloride via the caudal approach to induce analgesia of the paralumbar fossa (flank) in cattle. ⋯ Segmental dorsolumbar epidural analgesia with ketamine administered via multiple-port catheters by use of the caudal approach in cattle was feasible, and the cattle remained standing with minimal adverse effects. Further studies are necessary to determine whether this technique provides optimal conditions to allow surgery in standing cattle.
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To assess the effects of alterations in PaCO(2) and PaO(2) on blood oxygenation level-dependent (BOLD) signal intensity determined by use of susceptibility-weighted magnetic resonance imaging in brains of isoflurane-anesthetized dogs. ⋯ In isoflurane-anesthetized dogs, certain regions of gray matter appeared to have greater cerebrovascular responses to changes in PaCO(2) and PaO(2) than did others. Both PaO(2) and PaCO(2) should be controlled during magnetic resonance imaging procedures that involve BOLD signaling and taken into account when interpreting findings.