Hepato Gastroenterol
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A 51-year-old woman with a history of anemia, with negative upper and lower endoscopy results, underwent video capsule endoscopy; the small bowel was found negative but colonic study showed blood present in stools in the lumen. The patient was referred for a second colonoscopy that indicated positive for right colon cancer.
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Hepato Gastroenterol · May 2008
COMT gene val158met polymorphism in patients with dyspeptic symptoms.
The role of genetics in the susceptibility to functional dyspepsia (FD) is unclear. Catechol-O-methyltransferase (COMT) has been an important enzyme in brain gut axis and pain sensitivity. Polymorphism in codon 158 of the COMT gene influences its activity. This study aimed to clarify the association between COMT polymorphism and dyspepsia in a Japanese population. ⋯ The data suggest that the COMT genotype seems to influence the susceptibility of dyspepsia when it interacts with gender and age. The role of genetics in the development of dyspepsia needs to further evaluation.
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Hepato Gastroenterol · May 2008
Hepatectomy and pancreatectomy with combined vascular resection in patients with hepato-biliary and pancreas diseases at a single cancer institute.
In advanced cancers of hepatobiliary and pancreatic lesions, major vascular resection and reconstruction are necessary to accomplish curative resection, which may provide better patient outcomes. ⋯ Complete surgical resection (R0) combined with main vascular resection could be safely performed in many patients with disease of the hepatobiliary and pancreas, which achieved longer survival in some patients even in the advanced stage.
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Hepato Gastroenterol · May 2008
Comparative StudyThe use of different diagnostic modalities in diagnosing fistula-in-ano.
In this study, a comparison was made of the accuracy and clinical usefulness of clinical investigation, fistulography, and endorectal ultrasound with and without hydrogen peroxide in preoperative classification of the fistula-in-ano. ⋯ In this study, endorectal ultrasound with H2O2 was the most accurate diagnostic modality in the preoperative assessment of the fistula-in-ano. As it can provide valuable information that can influence the type of operative procedure, and because it is relatively cheap and available in almost all hospitals, it should be used prior to operative treatment in all patients with a fistula-in-ano.