Hepato Gastroenterol
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Hepato Gastroenterol · Sep 2012
Comparative StudyA retrospective analysis of ultralow anterior resection vs. abdomino-perineal resection for lower rectal cancer.
The aim of this study was to compare the oncological outcome of ultralow anterior resection (ULAR) and abdominoperineal resection (APR) for lower rectal cancer. ⋯ Ultralow anterior resection and abdominoperineal resection have similar long-term outcome in lower rectal cancer. In tumor local relapse, APR is more effective than ULAR, but in distant metastasis, it not better than ULAR.
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Hepato Gastroenterol · Jul 2012
Meta Analysis Comparative StudySingle-incision laparoscopic surgery vs. multiport laparoscopic surgery for colectomy: a meta-analysis of eleven recent studies.
Single-incision laparoscopic colectomy (SILC) is rapidly becoming the focal point of attraction for early adopters of minimally invasive surgery worldwide. The aim of this study was to compare SILC with multiport laparoscopic colectomy (MLC) when implemented by experienced laparoscopic surgeons. ⋯ SILC is a technically realistic and reliable approach with short-term results similar to those obtained with the MLC procedure. More large, prospective, randomized, controlled trials should be conducted to further compare the safety and efficacy of this approach.
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Hepato Gastroenterol · Jul 2012
Preoperative radiotherapy combined with S-1 for advanced lower rectal cancer: phase I trial.
S-1 based chemoradiation is the recommended treatment for rectal cancer; however, the optimal scheduling and dosing are not yet established. A Phase I study was conducted to determine the maximum tolerated dose (MTD) of S-1 with radiotherapy (RT). Endpoints were the toxicity profile of this regimen and to determine the recommended dose (RD). ⋯ The RD of S-1 with concurrent RT was determined to be 80mg/m2/day. Preoperative RT combined with S-1 was feasible and well tolerated.
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Hepato Gastroenterol · Jun 2012
Comparative StudyAdjuvant transarterial chemoembolization after curative resection of hepatocellular carcinoma: a non-randomized comparative study.
Prevention of recurrence is the most important strategy to improve long-term survival after resection of hepatocellular carcinoma (HCC). This comparative study aimed to evaluate the outcome of adjuvant transarterial chemoembolization (TACE) after hepatectomy. ⋯ Adjuvant TACE improved surgical outcome in those patients with risk factors of HCC recurrence.
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Hepato Gastroenterol · Jun 2012
Randomized Controlled TrialTerlipressin in the treatment of late phase catecholamine-resistant septic shock.
Norepinephrine, but also dopamine and epinephrine are recommended as first line vasopressors in the treatment of septic shock. In some patients, septic shock deteriorates and becomes to be resistant to catecholamines. In this situation, addition of vasopressin or terlipressin can be advantageous. The aim of our pilot study was to evaluate the impact of terlipressin on open label norepinephrine requirements and mortality. ⋯ Continuous terlipressin infusion was not effective in reducing norepinephrine consumption or in the mortality of patients, if administered in late phase of catecholamine refractory septic shock.