Hepato Gastroenterol
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Hepato Gastroenterol · Dec 1990
Specific cellular immune response in patients with Helicobacter pylori infection.
The leukocyte migration inhibition test was performed in 39 patients with Helicobacter pylori infection and in 38 patients without such infection. The culture of Helicobacter pylori was used as antigen. A highly significant inhibitory effect on leukocyte migration was found in patients with Helicobacter pylori infection. The results can be taken as proof of a systemic immune response to helicobacters at the cellular level in patients with Helicobacter pylori infection.
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Hepato Gastroenterol · Aug 1989
Review Comparative StudyComparative clinical results of ileal-pouch anal anastomosis and ileorectal anastomosis in ulcerative colitis.
The aim of the study was to compare the results of ileal-pouch anal anastomosis (IAA) and total abdominal colectomy with ileorectal anastomosis (IRA) in the treatment of ulcerative colitis. The number of patients included in the comparative trial was 104 (IAA) and 197 (IRA), respectively. ⋯ A factor favoring IAA was, among others, recurrence of proctitis after IRA which is more difficult to treat than the pouchitis occurring after IAA and is associated with a higher rate of secondary permanent end ileostomy; besides, IRA entails the risk of cancer developing in the rectal stump, while at the same time it is difficult to follow up these patients closely enough. IRA is indicated only if the diagnosis of ulcerative colitis is in doubt; if the patient is more than 60 years of age; and if IAA proves technically too difficult, IAA is usually preferable, however, if there is any doubt as to whether the patient is suffering from ulcerative colitis or Crohn's disease, ileorectostomy is preferred which does not preclude IAA at a later date in case of need.
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Among the pathological changes producing dysphagia, cysts are of only minor importance. Intramural pseudodiverticulosis of the esophagus as a consequence of cystic esophagitis with scarring of the submucosa and subsequent stenosis, has been observed more frequently in recent years. ⋯ Their removal presents no technical problems. It should be remembered that esophageal cysts might be the reason for dysphagia.