Minerva anestesiologica
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Corticosteroids are potent anti-inflammatory agents whose use has been life-saving in many diseases. Thus, it makes intuitive sense to use corticosteroids in septic shock, a disease where the inflammatory response is vigorously activated. Early studies examining the usage of corticosteroids in septic shock did not show any benefit, however, these studies administered very large doses. ⋯ Multi-center double blinded, randomized trials further added to the controversy without completely clarifying the issue. Moreover, the use of corticosteroids in critical illness must balance potential benefits with minimal side effects, however even such issues remain debatable as some studies show no untoward harm while other find the opposite. This review examines the use of corticosteroids in septic shock, discusses some of the shortcomings of the major clinical trials and outlines the most recent recommendations.
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Minerva anestesiologica · Feb 2011
ReviewSelective decontamination of the digestive tract as infection prevention in the critically ill. A level 1 evidence-based strategy.
Selective decontamination of the digestive tract (SDD) evolved into evidence-based medicine as a tool to prevent infections in critically ill patients. It significantly reduces mortality, pneumonia, bloodstream infections and the onset of resistance if the full four-component regimen is used. The use of only oral decontamination may reduce the incidence of pneumonia, but it has no significant impact on mortality. Moreover, the full SDD protocol significantly reduces the fecal carriage of multiresistant aerobic Gram-negative bacteria, whereas oral decontamination only is associated with increased carriage of multiresistant aerobic Gram-negative bacilli.
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Minerva anestesiologica · Feb 2011
Fast-track surgery: it is time for the anesthesiologist to get involved!
Fast-track methodology has been developed with the aim of improving postoperative recovery and reducing perioperative morbidity and mortality. A multidisciplinary approach involving surgeons, anesthesiologists, nurses and physiotherapists is necessary. While the surgical community has revised many of the standard principles used in clinical practice, anesthesiologists still need to contribute more to further optimize and facilitate recovery after surgery.
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Minerva anestesiologica · Feb 2011
The distance from the skin to the epidural and subarachnoid spaces in parturients scheduled for caesarean section.
The purpose of this study was to measure the skin to epidural space distance (SED), the skin to subarachnoid space distance (SSD) and the epidural to subarachnoid space distance (ESD) at the L3-4 interspace in parturients scheduled for caesarean section (CS) and to investigate whether any correlations exist between these distances and various physical and anthropometric parameters. ⋯ Measurements of SED, SSD and ESD in parturients and the correlations between these distances to various physical and anthropometric parameters may be of potential value for combined spinal-epidural anesthesia (CSEA) in parturients scheduled for CS.
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Minerva anestesiologica · Feb 2011
Closed tracheal suction and fluid aspiration past the tracheal tube. Impact of tube cuff and airway pressure.
This study investigated the effect of different tube cuff types and airway pressures on fluid leakage past the tracheal tube cuff during suction with a closed tracheal suction system (CTSS). ⋯ The use of PU tube cuffs and intermittent transient increases in cuff pressure during suction can effectively reduce fluid leakage past the tracheal tube during closed tracheal suctioning.