Minerva anestesiologica
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Minerva anestesiologica · Jun 2015
Ondansetron attenuates the decrease in blood pressure due to spinal anaesthesia in the elderly - a double blind, placebo-controlled study.
Ondansetron was effectively used to prevent spinal anesthesia-induced hypotension in the general population and women anesthetised for cesarean section. The aim of this study was to test the hypothesis that blocking type 3 serotonin receptors with intravenous ondansetron administration reduces hypotension and bradycardia induced by spinal anesthesia in elderly patients. ⋯ Administration of intravenous ondansetron prior to spinal anesthesia in geriatric patients attenuates the drop in the diastolic and mean arterial pressure without substantially affecting the systolic blood pressure.
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Minerva anestesiologica · Jun 2015
Multimodal neurological approach can lead the treatment in post-cardiac arrest persistent refractory status epilepticus.
Refractory status epilepticus (RSE) is a common challenge in the setting of post resuscitation care. We describe how multimodal neurological approach can lead treatment and improve the prognosis. ⋯ No evidence-based data exist to guide management of RSE in the setting of anoxic brain injury. Our cases emphasize the need for continuous active treatment led by a multimodal approach in order to improve neurological outcome.