Minerva anestesiologica
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Minerva anestesiologica · May 2018
Randomized Controlled TrialThe addition of continuous wound infusion of local anaesthetics to local infiltration in the management of postoperative pain and rehabilitation after total hip arthroplasty: a double-blind randomized controlled trial.
Total hip arthroplasty is one of the most common procedures in orthopedic surgery. We hypothesized that local infiltration of analgesia and continuous wound infusion of anesthetics in the first 72 hours after surgery could provide more effective postoperative analgesia with better rehabilitation. ⋯ The addition of continuous wound infusion of anesthetics to local infiltration analgesia provided an extended analgesic effect associated with good rehabilitation performance.
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Minerva anestesiologica · May 2018
Randomized Controlled TrialThe analgesic potency dose of remifentanil to minimise stress response induced by intubation and measurement uncertainty of surgical pleth index.
The aim of this study was to evaluate the analgesic potency dose of remifentanil to maintain Surgical Pleth Index (SPI) values at less than 50 after intubation in patients undergoing general anesthesia with target-controlled infusion of propofol and remifentanil. ⋯ The analgesic potency dose of remifentanil to maintain SPI values at less than 50 after intubation was 135.0 µg.
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Minerva anestesiologica · May 2018
ReviewPhysiology, intervention, and outcome: three critical questions about cerebral tissue oxygen saturation monitoring.
The balance between cerebral tissue oxygen consumption and supply can be continuously assessed by cerebral tissue oxygen saturation (SctO2) monitor. A construct consisting of three sequential questions, targeting the physiology monitored, the intervention implemented, and the outcomes affected, is proposed to critically appraise this monitor. The impact of the SctO2-guided care on patient outcome was examined through a systematic literature search and meta-analysis. ⋯ However, its effects on other neurocognitive outcomes remain unclear. These results need to be interpreted with caution due to the high risks of bias. Quality RCTs based on improved intervention protocols and standardized outcome assessment are warranted in the future.