Minerva anestesiologica
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Minerva anestesiologica · May 2019
Randomized Controlled TrialIntraoperative dexmedetomidine attenuates stress responses in patients undergoing major spine surgery.
Surgical stress induces stress hormone release and sympathetic hyperactivation, resulting in hemodynamic instability. Dexmedetomidine has sympatholytic and hemodynamic stabilizing effects. We investigated whether dexmedetomidine could attenuate stress responses in major spine surgery. ⋯ Intraoperative dexmedetomidine administration reduced stress hormone release and maintained the balance of the autonomic nervous system. Dexmedetomidine could attenuate surgical stress response without untoward hemodynamic adverse events.
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Minerva anestesiologica · May 2019
Editorial CommentIntraoperative nociception: "if you can't measure it, you can't manage it".
Abstract
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Minerva anestesiologica · May 2019
Editorial CommentPerioperative off-label use of gabapentinoids: Evidence-Based Medicine validated or not?
Abstract