Minerva anestesiologica
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Minerva anestesiologica · Sep 2019
Clinical TrialAutomated measurement of neutrophil CD64 expression for diagnosing sepsis in critically ill patients.
Although early identification of sepsis improves outcome, prompt and correct diagnostic remains often challenging. The expression of the high affinity immunoglobulin-Fc fragment receptor I CD64 on neutrophils is upregulated during acute inflammation. We here aimed at determining the usefulness of its rapid measurement in diagnosing sepsis. ⋯ This prospective study demonstrates the moderate performance of the neutrophil CD64 index, assessed through the Accellix-CD64® device, in diagnosing sepsis in the critically ill patient. However, repeat measurements improve its accuracy and may help to predict ICU-acquired infections.
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Minerva anestesiologica · Sep 2019
Observational StudySevoflurane sedation for weaning from mechanical ventilation in pediatric intensive care unit.
Light sedation is the prerequisite for weaning from mechanical ventilation. Our aim was to evaluate the technical feasibility and efficacy of sevoflurane delivered by anesthetic conserving device (ACD) for sedation of children during weaning from mechanical ventilation. ⋯ Sevoflurane administration by ACD is technically feasible in critically ill children. It provides sedation within the desired sedation interval 89% of time, with short time to extubation after termination of administration. Decrease in mean arterial pressure warrants good hemodynamic monitoring and optimization of preload. Longer sevoflurane sedation and higher ETsevo is associated with development of reversible psychomotor dysfunction.
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Minerva anestesiologica · Sep 2019
Comparative Study Observational StudyEffects of a physiotherapic program in patients on veno-venous extracorporeal membrane oxygenation. A 8 year single center experience.
To date, there is no agreement on the timing to perform a physical session in patients on veno-venous extracorporeal membrane oxygenation (VV-ECMO). We aimed to assess whether early physiotherapy (within the first week from ECMO start) could affect in-ICU mortality. ⋯ In patients on VV-ECMO support, physiotherapy is feasible and safe and that early physiotherapy, initiated within the first week from ECMO start, is associated with shorter duration of ECMO support and ICU length of stay.
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Minerva anestesiologica · Sep 2019
Editorial CommentLong-term outcome after VV ECMO: like the iceberg beneath the Titanic.
Abstract
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Minerva anestesiologica · Sep 2019
Editorial CommentPaying attention to patient self-inflicted lung injury.
Abstract