Minerva anestesiologica
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Minerva anestesiologica · Feb 2021
Observational StudySublingual sufentanil tablet system for the management of acute postoperative pain in a hospital setting: an observational study.
The use of a strong opioid with intravenous patient-controlled analgesia (IV-PCA) is recommended for postoperative pain, but its use is restricted due to technical problems. Other delivery systems, like sublingual PCA, with the sufentanil tablet system (SSTS) device, could overcome the safety concerns related to IV-PCA. ⋯ Under a real-life clinical practice setting, SSTS provides effective pain management and is easy to use for patients and nurses.
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Minerva anestesiologica · Feb 2021
Platelet morphological indices on ICU admission predict mortality in septic but not in non-septic patients.
Thrombocytopenia is associated with worse outcomes in critically ill patients. The clinical relevance of other platelets indices is less studied. We investigated the ability of the platelets distribution width (PDW) and the mean platelet volume (MPV) to predict mortality in critically ill patients. We hypothesized that the prognostic values of PDW and MPV could be different in septic and non-septic patients. ⋯ Platelet morphological indices are independent predictor of 90-day mortality in septic patients but not in non-septic patients. A combined analysis of platelets morphological indices and lactate in septic patients resulted in improved prediction of mortality.