Minerva anestesiologica
The most recent articles from:
Minerva Anestesiol
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Minerva anestesiologica · Aug 2013
Editorial CommentPerioperative administration of colloids: far from good?
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Minerva anestesiologica · Aug 2013
Observational StudyAmmonia plasma concentration and prolonged infusion of remifentanil in patients with acute kidney injury.
Glycine is an excipient of remifentanil and may induce side effects. To investigate glycine and ammonia concentration with the use of remifentanil in Intensive Care Unit patients with acute kidney injury (AKI) defined by a decrease in creatinine clearance above 50%. ⋯ Remifentanil was not associated with an accumulation of glycine or ammonia in patients with AKI. Plasma ammonia concentration was correlated with the mean rate of remifentanil and creatinine clearance. A 72-hours remifentanil infusion appeared safe for sedation of patients with AKI.