Minerva anestesiologica
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Minerva anestesiologica · Apr 2012
Use of pulse pressure variation to estimate changes in preload during experimental acute normovolemic hemodilution.
Acute normovolemic hemodilution (ANH) is an alternative to blood transfusion in surgeries involving blood loss. This experimental study was designed to evaluate whether pulse pressure variation (PPV) would be an adequate tool for monitoring changes in preload during ANH, as assessed by transesophageal echocardiography. ⋯ Changes in preload during ANH were detected by changes in PPV. ∆PPV was superior to ∆PAOP and ∆CVP to this end.
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Minerva anestesiologica · Apr 2012
Letter Case ReportsPrucalopride in a case of severe opioid induced constipation.
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Minerva anestesiologica · Mar 2012
Multicenter Study Clinical TrialCytochrome P450 polymorphism and postoperative cognitive dysfunction.
The etiology of postoperative cognitive dysfunction (POCD) remains unclear but toxicity of anesthetic drugs and their metabolites could be important. We aimed to assess the possible association between POCD after propofol anesthesia and various phenotypes owing to polymorphisms in cytochrome P450 encoding genes. ⋯ Polymorphisms in CYP2C19, or 2D6 genes do not seem to be related to the occurrence of cognitive dysfunction after non-cardiac surgery in patients anesthetised with propofol.