Minerva anestesiologica
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Minerva anestesiologica · Nov 1999
Clinical TrialTotal intravenous anesthesia with propofol and remifentanil for elective non-cardiac surgery.
Remifentanil is a highly effective mu opioid agonist with predictable pharmacokinetics and a close concentration-effect relationship. Moreover, studies on anesthetic drugs interactions show that optimal propofol concentrations decrease more significantly with remifentanil as compared with other opioids and recovery appears to be much faster than when propofol is combined with other opioids combinations. This intervention study was designed to evaluate the efficacy of propofol combined with remifentanil in elective non cardiac inpatient surgery. ⋯ When combined with propofol, remifentanil effectively provided for profound analgesia during surgery, stable anesthetic conditions, simplicity of use and predictable recovery.
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Minerva anestesiologica · Oct 1999
Randomized Controlled Trial Comparative Study Clinical TrialEffects of diclofenac and intra-articular morphine/bupivacaine on postarthroscopic pain control.
This study was undertaken to compare analgesic effects and requirements for supplemental analgesic therapy after knee arthroscopy in patients given intraarticular morphine/bupivacaine, diclofenac i.m., or both compared with placebo. ⋯ The combination of diclofenac i.m. and intraarticular morphine/bupivacaine appears to be the most beneficial analgesic combination due to its lower VAS scores and supplemental analgesic requirements in the postoperative period.
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Minerva anestesiologica · Oct 1999
Comparative Study Clinical Trial[Epidural analgesia for painless delivery. Our experience].
We know that a stress condition causes hormonal responses (cortisol, prolactin, TSH, ACTH, catecholamines, beta-endorphines). This hormonal "storm" causes metabolic and haemodynamic changes that can get worse postoperative outcome as well as birth. Analgesia for labour is an anesthesiological procedure which spreading in Italy resulted very difficult, for instance, especially in southern Italy, "old popular believes" (such as paralysis risk after lumbar puncture, Post-Dural Puncture Headache (PDPH) and the confusion between epidural and subdural anesthesia). ⋯ APGAR-score in new-borns with epidural analgesia in higher than new-born without epidural analgesia; furthermore, patients who choose painless labour expressed a better judgement than women who refused epidural analgesia.
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Minerva anestesiologica · Oct 1999
Randomized Controlled Trial Multicenter Study Comparative Study Clinical Trial[Comparison of manual infusion of propofol and target-controlled infusion: effectiveness, safety and acceptability].
Diprifusor TCI is a newly developed target-controlled system for the infusion of propofol. Purpose of this study is to evaluate the acceptability, efficacy and safety of Diprifusor TCI in comparison with the manually controlled technique. ⋯ The TCI technique is effective and safe, and has a better acceptability than the manually controlled infusion technique.
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Minerva anestesiologica · Oct 1999
Case ReportsProlonged mivacurium-induced neuromuscular block. Case report.
A 38-year-old white male patient was admitted to the hospital for elective surgery. General anesthesia was performed with propofol, alfentanil, nitrous oxide and mivacurium as neuromuscular blocker. ⋯ After mivacurium administration the first signs of recovery from neuromuscular block were observed after 255 min. The tracheal tube was withdrawn after 410 min from mivacurium administration, at this time the T1 was 80% of the control values and 7 min later the T1 reached 98%.