Minerva anestesiologica
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Minerva anestesiologica · Oct 1995
Case Reports[Thrombocytopenia and thrombophilic state in heparin therapy].
The authors report two clinical cases of thrombocytopenia and thrombosis which occurred during profilaxys and therapy with heparin. The mechanisms involved are reviewed and the possible therapeutic role of heparin-like drugs is discussed according to data presented in the international literature.
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Minerva anestesiologica · Sep 1995
Case Reports[Tetraplegia and acute respiratory insufficiency from an ischemic cervical medulla lesion after cocaine use. A clinical case].
The article deals with a case report on tetraplegia and acute respiratory failure following ischemic damage of the spinal medulla in the cervical tract due to cocaine assumption. The ischemic damaged produced by cocaine usually injure the great vessels of the cranial base. The case report is particular because of the area and the seize of the injured vessel. Finally, the most important hypotheses about the pathogenesis in the ischemic cerebrovascular cocaine-induced damages are debated.
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Minerva anestesiologica · Sep 1995
Randomized Controlled Trial Clinical Trial[Prevention of postoperative nausea and vomiting with ondansetron: a prospective, randomized, double-blind study in 90 patients].
Postoperative nausea and vomiting (PONV) are among the most common complications in surgical patients. In this prospective, double blind, parallel group study we compare the prophylactic antiemetic efficacy of ondansetron versus placebo in 90 patients undergoing general balanced anaesthesia. The patients were stratified according to the kind of surgery and randomly allocated to three treatment groups: 30 patients (Group A) received ondansetron 4 mg i.v. 1 hour before the induction of anaesthesia and placebo 1 hour before the end of surgery; 30 patients (Group B) received placebo 1 hour before the end of anaesthesia and ondansetron 4 mg i.v. 1 hour before the end of surgery; 30 patients (Group C-control group) received placebo in both the administrations. ⋯ Although the patients in Group A showed a lower incidence of PONV in comparison to the patients in Group B, such differences proved to be not statistically significant. No adverse effects in relation to drug administration were observed. We conclude that ondansetron 4 mg i.v. is safe and effective in preventing PONV in the surgical patients, particularly when administered before the induction of anaesthesia.
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Minerva anestesiologica · Sep 1995
Clinical TrialVenous-arterial PCO2 and pH gradients in acutely ill postsurgical patients.
To investigate the venous-arterial PCO2 gradient, and the mixed venous blood acid-base status together with the oxygen transport variables in a group of acutely ill postsurgical patients. ⋯ This study suggests that in acutely ill postoperative patients increased venous-arterial PCO2 and pH gradients are directly and principally related to the reduction in blood flow and are both suggestive of low-flow state.
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Minerva anestesiologica · Jul 1995
Randomized Controlled Trial Comparative Study Clinical Trial[Patient-controlled postoperative analgesia in orthopedic surgery: epidural PCA versus intravenous PCA].
To evaluate both effectiveness and incidence of side effects of two techniques of postoperative pain treatment: intravenous and epidural PCA. ⋯ Our data show a better control of postoperative pain arising from total hip replacement during PCEA when compared to PCA. It should be emphasized that incident pain is far more decreased by PCEA, so that this technique is particularly indicated when an early postoperative mobilization is required.