Minerva anestesiologica
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Minerva Anestesiol
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Minerva anestesiologica · Jan 2023
General anesthesia in early childhood and possible association with autism: a population-based matched cohort study.
In experimental animal studies, exposure to general anesthesia in early childhood may results in changes in infant brain morphology and behavior, potentially leading to the development of autistic behaviors in the long-term. However, in clinical studies the role of exposure to general anesthesia in early childhood and the risk of autism is unknown. ⋯ Exposure to general anesthesia in early childhood was associated with an increased risk of autism or autism spectrum disorder. Future studies are needed to asses if general anesthesia may cause autism or if the association is due to other factors.