Minerva anestesiologica
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Minerva anestesiologica · Mar 2000
Randomized Controlled Trial Comparative Study Clinical Trial[Comparative study of the effects of morphine and tramadol in the treatment of postoperative pain].
To compare morphine and tramadol in the treatment of postoperative pain (POP), using a system of Patient Controlled Analgesia (PCA). ⋯ Tramadol determines pain relief similar to morphine, with the advantage that it does not lead to abuse, tolerance or addiction.
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Minerva anestesiologica · Jan 2000
Randomized Controlled Trial Comparative Study Clinical Trial[Emergence and postoperative course after anesthesia with sevoflurane versus propofol].
To compare the postoperative period, with particular regard to occurrence of adverse effects at the time of emergence from anaesthesia, recovery parameters, any post-surgical analgesia requirements and laboratory tests changes in 80 ASA I and II patients undergoing sevoflurane or propofol anaesthesia for elective extracavity surgery. ⋯ Significant differences of postoperative adverse effects and laboratory tests changes were not recorded in both groups of anaesthetics.
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Minerva anestesiologica · Jan 2000
Randomized Controlled Trial Comparative Study Clinical Trial[The effect of antithrombin iii concentrations during cardiopulmonary surgery].
Evaluation of influence of pre-op continuous e.v. heparin infusion in patients undergoing urgent myocardial surgical revascularization, on the anticoagulation threshold needed for cardiopulmonary bypass. Analysis of the efficacy of ATIII substitutional therapy to allow best ACT values during extracorporeal circulation, and to reduce intra and post-op bleeding and need for homologus transfusion. ⋯ Intraoperative administration of ATIII can reduce most problems due to heparinization of the extracorporeal circuit, such as onset of fibrinolysis, CID and platelets depletion or inactivation causing intra and post-op massive bleeding.
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Minerva anestesiologica · Jan 2000
Randomized Controlled Trial Comparative Study Clinical TrialInterscalene brachial plexus anesthesia with either 0.5% ropivacaine or 0.5% bupivacaine.
To compare intra- and postoperative clinical properties of interscalene brachial plexus block performed with either 0.5% ropivacaine or 0.5% bupivacaine. ⋯ This study confirmed that 0.5% ropivacaine has clinical properties similar to those of 0.5% bupivacaine, when used for interscalene brachial plexus block, providing similarly long duration in postoperative pain relief. Compared with bupivacaine, ropivacaine has the further advantage of a lower potential for central nervous system and cardiovascular toxicity.
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Minerva anestesiologica · Nov 1999
Randomized Controlled Trial Comparative Study Clinical Trial[Loco-regional block in ophthalmic surgery: single drug or drug combination with hyaluronidase? Randomized prospective study].
The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia were included in this prospective, randomized and partially blind study. Peribulbar blockade was performed on 199 patients (group P). Ninety-nine of them received a mixture of local anaesthetics and hyaluronidase (sub-group M), while 100 received bupivacaine alone (sub-group B). Retrobulbar blockade was performed on 200 patients (group R): 100 of them received the mixture with hyaluronidase (sub-group M), while 100 received bupivacaine (sub-group B). The interval between anaesthesia and motor blockade (onset time), the presence of residual ocular movements, the need of further anaesthesia, the quality of anaesthesia, the ocular tone, the length of anaesthesia and possible complications were registered. ⋯ Local anaesthetics mixture with hyaluronidase associated with peribulbar blockade presents the advantages of rapidity, duration and better quality without the risks of retrobulbar blockade side effects.