Turk Neurosurg
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Randomized Controlled Trial
Neuroprotective Effects of Erythropoietin in Patients with Severe Closed Brain Injury.
Our research was focused on the neuroprotective function of erythropoietin (Epo) in patients with severe closed traumatic brain injury (TBI). ⋯ The study provides evidence of lower mortality and better neurological outcome for the patients who received Epo increasing the possibility that Epo therapy could be used in clinical practice, limiting neuronal damage induced by TBI.
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The surgical treatment of spinal metastases is still controversial. Due to developments in diagnostic imaging there has been a great evolution in minimally invasive surgical techniques for the spinal surgery. Most of the patients with spinal metastases are debilitated and under high risk of major surgical morbidity and mortality. ⋯ Minimal invasive techniques represent major advance in minimizing approach related morbidity in the treatment of spinal tumors. Because of the evolution of minimally invasive surgical techniques for the spinal surgery, minimally invasive techniques are alternative treatment to standard open approaches for the treatment of metastatic spinal tumors. Due to less complication rates there has been a trend toward the minimalization of spine surgery.
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This study aimed to investigate the operative procedure for neuroendoscope-assisted microscopic resection of petroclival meningioma to improve prognosis. ⋯ Neuroendoscope-assisted microscopic resection for petroclival meningioma can improve the total and subtotal resection rates of the tumor. Moreover, this method does not increase postoperative short-term and long-term complications.
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The "trephined" syndrome is a relatively rare complication after a large skull bone defect, consisting of a sunken skin above the bone defect with neurological symptoms such as severe headaches, mental changes, focal deficits, or seizures. Emerging data show improvements in the patients' neurological status after cranioplasty, i.e. the surgical intervention to repair cranial defects. ⋯ His motor and neuropsychological status greatly improved after cranioplasty. Our results confirmed previous reports that cranioplasty may significantly improve neuropsychological and motor function, as evaluated by specific tests, in patients with skull bone defects, and even in patients with DOC.
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Randomized Controlled Trial
Enteral Nutritional Support in Patients with Head Injuries After Craniocerebral Surgery.
To explore the effect of early enteral (EN) and parenteral nutritional (PN) support on head-injured patients after craniocerebral surgery. ⋯ Early EN support is superior to PN support in head-injured patients after craniocerebral surgery.