Turk Neurosurg
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Remote intracranial hemorrhages after craniotomy or craniectomy may rarely develop. As the sparse literature on this phenomenon has focused on contralateral intraparenchymal and epidural clots, only seven cases of postoperative contralateral acute subdural hematomas have been reported in the literature. We presented two patients who developed contralateral acute subdural hematomas after surgical evacuation of their initial hematomas. ⋯ A right decompressive craniectomy and subdural hematoma evacuation were performed; however, the brain expanded towards the craniectomy site. An emergency CT scan revealed a left acute subdural hematoma. We also reviewed the literature and discussed about these characteristics.
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This study aims to evaluate how analgesia-sedation causes alterations of HLA-DR and cytokines (IL-10 and IL-6) in patients undergoing cerebral angiography for several cerebral vascular diseases. ⋯ We suggest that the effects of fentanyl and midazolam on the immune response are the reflection of the effects by the monocyte, mHLA-DR expression. In the future, depending on the immunological status of the patients, different anesthetic applications including the new anesthetic agents that will be able to decrease immune system suppression will be required.
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The aim was to investigate whether dexmedetomidine had a toxic effect on cerebral neurons when it was administered centrally into the cerebrospinal fluid by the intracisternal route. ⋯ In conclusion, dexmedetomidine had a toxic effect on cerebral neurons when it was administered centrally into the cerebrospinal fluid by the intracisternal route.
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In this study, the effects of lornoxicam on the prevention of secondary brain injury via the apoptotic pathway were studied in a rat model of head injury. ⋯ Lornoxicam did not prevent apoptosis in this rat model of brain trauma but causes a decrease.
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The purpose of this study was to determine the possible protective effects of captopril treatment against apoptosis in the brain induced by burn injury. ⋯ Captopril has beneficial effects in burn injury and should be assessed as a therapeutic agent in the management of this condition.