World Neurosurg
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The use of nanoparticles in diagnostic imaging is rapidly gaining utility and acceptance. A handful of iron oxide nanoparticle compounds have already been approved by the U. S. ⋯ The ability of these particles to interact with cellular biology at a molecular level does have theoretical injurious potential. As with any medical intervention, its relative risks must be clearly understood. This article discusses the safety profile and potential toxicities of nanoparticles as used in diagnostic imaging, and serves to inform the prescribing physician of relative and potential risk to the patient.
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To investigate the learning and memory impairments at acute phase after mild traumatic brain injury (TBI) in Sprague-Dawley rats and its relationship with the expression of Arp2. ⋯ This study demonstrated that impairments of learning and memory function in the acute phase after mild TBI may be induced by a reduction in Arp2 expression.