World Neurosurg
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Randomized Controlled Trial Comparative Study
Prone versus sitting position in neurosurgery - differences in patients' hemodynamic management.
Neurosurgery in general anesthesia exposes patients to hemodynamic alterations in both the prone and the sitting position. We aimed to evaluate the hemodynamic profile during stroke volume-directed fluid administration in patients undergoing neurosurgery either in the sitting or the prone position. ⋯ The sitting position does not require excess fluid treatment compared with the prone position. HES is slightly more effective than RAC in achieving comparable hemodynamics, but the difference might be explained by patient weight. With goal-directed fluid administration and moderate use of vasoactive drugs, it is possible to achieve stable hemodynamics in both positions.
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The oncogenesis and biologic behaviors of benign glandular schwannoma have not been clinically unveiled because of its rarity and variability. ⋯ Therefore, the morphologic and immunohistochemical findings support the diagnosis of benign glandular schwannoma.
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Review Case Reports
Characteristics of Rosai-Dorfman Syndrome Primarily Involved in the Central Nervous System: A Three-Case Report and Review of Literature.
This study aimed to summarize the clinical characteristics of Rosai-Dorfman disease primarily involving the central nervous system and to explore diagnosis and treatment. ⋯ Rosai-Dorfman disease with multiple lesions primarily involving the central nervous system is rare. Imaging characteristics are similar to meningiomas, and the pathological features include lymphocytes and plasma cells reaching tissue cells with large volume and abundant cytoplasm. Surgery is the preferred treatment, as the effects of steroid administration and radiotherapy are not apparent.
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Meta Analysis
Meta-analysis of Microarray-Based Expression Profiles to Identify Differentially Expressed Genes in Intracranial Aneurysms.
To gain comprehensive insight into the molecular mechanism of formation and rupture of intracranial aneurysms (IAs). ⋯ Inflammation, immune response, and loss of contractile vascular smooth muscle cells could potentially contribute to the formation of IAs, whereas the role of angiogenesis and vascular remodeling in IA formation and rupture needs further exploration.
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The aim of this systematic review was to compare the halo and hard collar in the management of adult odontoid fractures. ⋯ For the most common clinical scenario, the halo and collar have similar failure rates, such that the higher morbidity associated with the halo may not be justified, especially in elderly patients. Malunion usually represents a stable clinical outcome, and surgery is rarely required. Prospective randomized studies are needed to more definitively compare the devices.