World Neurosurg
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All interbody fusions are associated with a risk of subsidence. In the case of lateral lumbar interbody fusion (LLIF), an interbody device that spans the apophyseal rings reduces subsidence. Small interbody device size, aggressive end plate preparation, and poor bone quality are contributors to subsidence. The goal of this study was to analyze the perioperative morbidity, particularly the timing of subsidence (intraoperative vs. postoperative), associated with transpsoas LLIF. ⋯ As LLIF becomes more common, it is important to better understand common complications, such as subsidence, and the specific rates at which they occur. A unique finding of exclusive intraoperative subsidence was observed. The use of cage size to obtain segmental lordotic correction and indirect decompression must be weighed against the potential risk of subsidence.
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Cerebral hyperperfusion syndrome, which carries a potential risk of intracranial hemorrhage, is a rare and overlooked condition in the setting of subarachnoid hemorrhage (SAH). ⋯ This is the first report to describe postischemic cerebral hyperperfusion syndrome after symptomatic vasospasm detected using sequential single-photon emission computed tomography during the acute stage of SAH. Early diagnosis of this rare phenomenon is crucial given the necessity to lower blood pressure for preventing hemorrhagic complications, which is contrary to the usual management of patients with vasospasm.
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Long noncoding RNAs (lncRNAs) are a large group of noncoding RNAs 200 nucleotides long. lncRNAs that function as regulatory factors have been identified for several complex cellular processes, such as cell death, growth, differentiation, apoptosis, epigenetic regulation, and so on. Many lncRNAs have altered expression and are likely to play a functional role in oncogenesis. ⋯ This review summarizes recent progress in the study of lncRNAs on the pathogenesis of pituitary tumors. We cover the latest results associated with this role and highlight the therapeutic possibilities for pituitary adenomas.
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Atlantoaxial spine surgery is a challenge to spinal surgeons because of its proximity to neurovascular structures. This study aimed to identify and analyze the scientific publications in atlantoaxial spine surgery from different countries and institutions. ⋯ The atlantoaxial spine surgery literature has grown continuously in recent years. The United States is the largest contributor in this field. Fixation and fusion are the most common areas, and fixation-related studies should be closely followed. The screw-rod fixation system is becoming increasingly popular.
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Little attention has been given to the retroverted dens within the existing medical literature. However, this finding can have a clinical impact, especially in patients with Chiari malformation type I (CM1), as it can have consequences for further treatment. ⋯ A greater degree of dens angulation can lead to neurologic symptoms secondary to spinomedullary compression. Therefore, correct measurements are essential as such findings can influence presurgical planning.