World Neurosurg
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Review Case Reports
Misdiagnosis and delay of diagnosis in hemorrhagic meningioma: a case series and review of the literature.
To evaluate the clinicoradiologic characteristics of hemorrhagic meningiomas (HMs) that are missed or misdiagnosed on radiologic imaging studies. ⋯ Our study showed that in patients with HM with inadequate imaging evaluation, a small tumor associated with massive hematoma and atypical imaging features was more likely to be misdiagnosed.
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Review Meta Analysis Comparative Study
Comparison of interventions for cervical ossification of posterior longitudinal ligament: a systematic review and network meta-analysis.
To summarize the literature and systematically evaluate outcomes for ossification of posterior longitudinal ligament interventions including anterior cervical corpectomy and fusion (ACCF), anterior controllable antedisplacement and fusion (ACAF), laminoplasty (LP), and laminectomy with fusion (LF). ⋯ Japanese Orthopaedic Association score outcomes indicated that ACCF was superior to LP and LF. ACAF had the largest cervical lordosis among all procedures. ACCF showed a higher incidence of overall complications compared with ACAF and LP.
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Review Meta Analysis
Effects of various therapeutic agents on vasospasm and functional outcome following aneurysmal subarachnoid hemorrhage - Results of a network meta-analysis.
Vasospasm and delayed ischemic neurologic deficits are the leading causes of morbidity and mortality after aneurysmal subarachnoid hemorrhage (aSAH). Several therapeutic agents have been assessed in randomized controlled trials for their efficacy in reducing the incidence of vasospasm and improving functional outcome. The aim of this network meta-analysis is to compare all these therapeutic agents for their effect on functional outcome and other parameters after aSAH. ⋯ Our analysis showed that nicardipine prolonged-release implants and cilostazol were associated with the best chance of improving favorable outcome and mortality in patients with aSAH. However, larger multicentric studies from other parts of the world are required to confirm these findings.
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Review Meta Analysis
A Systematic Review and Meta-Analysis of Statins in Animal Models of Intracerebral Hemorrhage.
Intracerebral hemorrhage (ICH) is a severe form of stroke with limited treatment options. Statins have shown promise as a therapy for ICH in animal and human studies. We systematically reviewed and assessed the quality of preclinical studies exploring statin-use after ICH to guide clinical trial decision-making and design. ⋯ Behavioral outcomes in ICH were found to consistently improve with administration of statins in preclinical studies suggesting that statin therapy may be suitable for randomized clinical trials in humans. In addition, the STAIR criteria can be modified to effectively evaluate preclinical studies in ICH.