World Neurosurg
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Our aim was to re-evaluate the h-index of neurosurgical units in the United Kingdom and Ireland because it was 5 years since it was last reported. ⋯ The h-index for neurosurgical units is the most reliable bibliometric, which shows the academic standing and correlates well with amount of research grant obtained and size of department. It is particularly useful when calculated for the most recent 10-year and 5-year periods. Neurosurgical units change their rankings over time and, therefore, it is important to update the tables periodically. We propose an online database with open access showing all h-index and bibliometric data for neurosurgical units in the United Kingdom and Ireland. This database could provide a live and dynamic report of the academic standings of those units and could be used for grant applications and reviews.
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Perfusion abnormalities due to vasospasm remain a major cause of morbidity and mortality in subarachnoid hemorrhage (SAH). Despite a large number of clinical trials, therapeutic options with strong evidence for prevention and treatment of cerebral vasospasm are rare. In this study, we aimed to evaluate the neuroprotective effect of salubrinal (SLB) in endoplasmic reticulum stress-induced apoptosis, a catastrophic consequence of vasospasm. ⋯ SLB, selective inhibitor of eIF2α dephosphorylation, and NMN, a calcium channel blocker, can ameliorate SAH-induced damage. Inhibition of eIF2α dephosphorylation and enhanced VEGF-A production with SLB may protect brain tissue from apoptosis.