World Neurosurg
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Review Meta Analysis
Recurrent Cushing's disease: An extensive review on pros and cons of different therapeutic approaches.
Recurrent Cushing disease (CD) is characterized by the reappearance of clinical and hormonal aspects of hypercortisolism that occur more than 6 months after an initial post-treatment remission. ⋯ Compared MT and TSS, RT has a statistically lower rate of remission. Although there is robust superiority of surgery over RT, interpretation of MT data must considered with caution due to the small number of included cases and wide CI range.