World Neurosurg
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This study aimed to characterize long-term cerebral perfusion pressure (CPP) trajectory in traumatic brain injury (TBI) patients and construct an interpretable prediction model to assess the risk of unfavorable CPP evolution patterns. ⋯ This study identified 2 CPP trajectory groups associated with elevated risk and 3 with reduced risk. PaCO2 might be a strong predictor for the unfavorable CPP class. The ANN model achieved the primary goal of risk stratification, which is conducive to early intervention and individualized treatment.
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Anterior temporal lobectomy (ATL) is the most common surgical treatment for temporal lobe epilepsy (TLE), and Stereoelectroencephalography (SEEG) plays a critical role in precisely localizing the epileptogenic zone (EZ). This study aimed to explore the effect of SEEG on the long-term outcomes of different side ATL. ⋯ Some TLE patients encounter challenges in localizing the EZ through non-invasive evaluation, necessitating the use of SEEG for precise localization. Furthermore, their seizure outcomes after surgery can be the same with the patients who have a clear epileptogenic zone in non-invasive evaluation. And SEEG patients can achieve a more stable long-term prognosis than non-SSEEG patients.
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GSWTH in children remain an underexplored area and all clinical guidelines extrapolated from adult experiences. A key challenge in treating these patients is age stratification, as pediatric survival rates are notably higher than in adults. The objective of the study is to compare two groups of patients based on the severity of their condition and to analyze the impact of various factors on the outcomes of these conditions. ⋯ The findings emphasize the importance of a multifactorial approach in children with GSWTH, highlighting its effectiveness for precise outcome prediction.
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Addiction is a serious spiral where negative events or relationships triggers a craving even when the situation is caused by the addiction in the first place. Nucleus Accumbens (NAcc) is identified as an important hub for the neural pathways involved in the addictive behavior. Stimulation of this structure was demonstrated to be beneficial for addiction previously, but radioneuromodulation was never investigated until today. This study aimed to investigate if radioneuromodulation of the nucleus accumbens has any effect on alcohol addiction. ⋯ This study indicates that nucleus accumbens radioneuromodulation, although not significantly affecting baseline consumption, reduces intake when an aversive stimulus is involved, implying improved self-control.