Kardiologiya
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Classical parasystoles are described of which the main signs are: variation of the coupling intervals, multiplicity of interectopic intervals, presence of fused ECG complexes. A detailed description of intermittent parasystolia is given. ⋯ The possible mechanisms of fusion of the main and the parasystolic rhythms are described in detail. A detailed table of differential diagnosis of extrasystole and parasystole is given.
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Comparative Study
[Erythrocyte coagulating and fibrinolytic activity in chronic ischemic heart disease].
It is shown that the erythrocytes of patients suffering from chronic ischaemic heart disease have normal or increased procoagulant, decreased anticoagulant and fibrinolytic activity, i.e. they enhance the increased coagulating and decrease the fibrinolytic potential of plasma in this group of patients. Addition of syncumar to the combined treatment causes certain decrease of the erythrocyte hypercoagulation potential, though it still remains marked. The fibrinolytic activity of plasma and erythrocytes remains unchanged.
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The difference in hemoglobin affinity for oxygen in blood of the coronary sinus and in mixed venous blood was shown in dog experiments. The lower affinity of hemoglobin for blood flowing from the heart causes greater deoxidation of oxyhemoglobin. ⋯ On the grounds of in vitro experiments it is suggested that this effect is mediated by adenosine 3,5-cyclic monophosphate entering the blood. The author discusses the importance of the flow rate of blood and adenosine 3,5-cyclic monophosphate as factors responsible for the specific features of the regulation of hemoglobin affinity to oxygen within organs and the possible ethiopathogenetic significance of increased hemoglobin affinity for oxygen in the development of myocardial hypoxia.
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Fifty patients with arrhythmia of the extrasystole type were examined by means of functional tests (atropine and physical exertion). Parasystole was revealed in 40 and extrasystole in 10 patients. ⋯ Reduction of the relative value of the longest pre-ectopic interval or increase of this interval by less than 10 per cent in the test was observed in extrasystole, an increase of the relative value of this interval by more than 10 per cent was encountered in parasystole. In cases with bigeminal rhythm, reduction of the absolute value of the longest pre-ectopic interval in the tests was characteristic of extrasystole while its increase was characteristic of parasystole.