Journal of the neurological sciences
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Sexual problems are common in Parkinson's disease and contribute to poor quality of life of patients and partners. Nonmotor and motor disease manifestations can affect sexual function. This article reviews the progressive and multidimensional sexual manifestations and provides practical suggestions for taking sexual history and treating sexual problems, which may enable clinicians to contribute to the sexual wellbeing of patients.
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Our objective was to assess which clinical factors contribute most to the impairment of instrumental activities of daily living (IADL) in patients with dementia in Parkinson's disease (PDD) as compared to age- and dementia duration-matched patients with Alzheimer's disease (AD). ⋯ Our pilot study results show that motor deficits remain the major contributor to IADL impairment in PDD.
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The choice of a scale has important implications for the results of clinical research, including epidemiological and treatment studies. In addition to the requirements for any clinical scale, evaluation of rating scales for depression and apathy in Parkinson's disease (PD) faces additional challenges, reflecting the overlap of syndromes, controversies on the concept particularly of apathy, fluctuations related to medication, and difficulties in assessment. ⋯ Scales for screening need to have different properties than scales for rating severity. Overall, there is no perfect scale, but the choice of scale needs to take into account clinimetric properties, validity in the sample examined, content and purpose.