The Journal of pediatrics
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The Journal of pediatrics · Feb 2011
Case ReportsCyclophosphamide for rapid-onset obesity, hypothalamic dysfunction, hypoventilation, and autonomic dysregulation syndrome.
Patients with rapid-onset obesity, hypothalamic dysfunction, hypoventilation, autonomic dysregulation, and neural crest tumor syndrome have poor long-term outcomes. We report a patient who was treated successfully with high-dose cyclophosphamide immunoablation. This experience offers a novel therapeutic approach and an indirect insight into the underlying pathogenesis of this syndrome.
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The Journal of pediatrics · Feb 2011
Oxygen supplementation in the delivery room: updated information.
Resuscitation is the most common procedure performed in neonatology. However, new contributions based on scientific evidence challenge the traditional procedures. Of these new contributions, the use of room-air instead of 100% oxygen and titration of the oxygen inspiratory fraction according to oximetry and heart rate represent a new approach in the resuscitation of both term and preterm newborns.