The Journal of pediatrics
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The Journal of pediatrics · Nov 2013
Root causes, clinical effects, and outcomes of unintentional exposures to buprenorphine by young children.
To characterize the rates, root causes, and clinical effects of unintentional exposures to buprenorphine sublingual formulations among young children and to determine whether exposure characteristics differ between formulations. ⋯ Unintentional exposure to buprenorphine can cause central nervous system depression, respiratory depression, and death in young children. Exposure rates to film formulations are significantly less than to tablet formulations. Package and storage deficiencies contribute to unintentional exposures in young children.
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The Journal of pediatrics · Nov 2013
Psychological and quality of life outcomes in pediatric populations: a parent-child perspective.
To compare the levels of quality of life (QoL) and psychological adjustment of children with different chronic health conditions with healthy children; to compare the QoL of parents of children with a chronic condition with parents of healthy children; and to examine the role of parents' QoL and children's psychological adjustment (ie, internalizing/externalizing problems) on children's QoL. ⋯ Children with chronic conditions, particularly epilepsy and obesity, are at increased risk for maladjustment. A routine assessment of QoL and psychological functioning should be performed in these children to better understand how specific conditions affect the lives of children with chronic conditions and their families. Family-oriented pediatrics should be considered, particularly in the treatment of obesity.
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The Journal of pediatrics · Nov 2013
Cognitive features that distinguish preschool-age children with neurofibromatosis type 1 from their peers: a matched case-control study.
To examine the cognitive functioning of 40-month-old children with neurofibromatosis type 1 (NF1). ⋯ After accounting for potentially confounding variables of age, sex, and maternal years of education, young children with NF1 have significantly poorer intellectual functioning, expressive language, and visual perception. These cognitive features that distinguish young children with NF1 from healthy peers can be detected in the preschool age group and are likely to impact on learning and performance during early school years. These areas should be targeted for intervention to maximize the developmental outcomes of young children with NF1.